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Loss-of-Function Genetic Screening Identifies Aldolase A as an Essential Driver for Liver Cancer Cell Growth Under Hypoxia.

Niu Y, Lin Z, Wan A, Sun L, Yan S, Liang H, Zhan S, Chen D, Bu X, Liu P, Chen C, He W, Lu X, Wan G*.

Hepatology. 2021 Sep;74(3):1461-1479.·2021·DOI

RNA-binding protein RALY reprogrammes mitochondrial metabolism via mediating miRNA processing in colorectal cancer.

Sun L#, Wan A#, Zhou Z, Chen D, Liang H, Liu C, Yan S, Niu Y, Lin Z, Zhan S, Wang S, Bu X, He W, Lu X*, Xu A*, Wan G*.

Gut. 2021 Sep;70(9):1698-1712.·2021·DOI

Design and Discovery of Natural Cyclopeptide Skeleton Based Programmed Death Ligand 1 Inhibitor as Immune Modulator for Cancer Therapy.

Sun H, Chen D, Zhan S, Wu W, Xu H, Luo C, Su H, Feng Y, Shao W, Wan A, Zhou B, Wan G*, Bu X*.

J Med Chem. 2020 Oct 8;63(19):11286-11301.·2020·DOI

RNA m6 A methylation regulates sorafenib resistance in liver cancer through FOXO3-mediated autophagy.

Lin Z, Niu Y, Wan A, Chen D, Liang H, Chen X, Sun L, Zhan S, Chen L, Cheng C, Zhang X, Bu X, He W*, Wan G*.

EMBO J. 2020 Jun 17;39(12):e103181.·2020·DOI