孙蕾

Publications

2025

Decoding the m6A epitranscriptomic landscape for biotechnological applications using a direct RNA sequencing approach.

Liu C#, Liang H#, Wan AH#, Xiao M#, Sun L#, Yu Y, Yan S, Deng Y, Liu R, Fang J, Wang Z*, He W*, Wan G*.

Nat Commun. 2025 Jan 18;16(1):798.·2025·DOI

2024

A multidimensional platform of patient-derived tumors identifies drug susceptibilities for clinical lenvatinib resistance.

Sun L, Wan AH, Yan S, Liu R, Li J, Zhou Z, Wu R, Chen D, Bu X, Ou J, Li K, Lu X, Wan G*, Ke Z*.

Acta Pharm Sin B. 2024 Jan;14(1):223-240.·2024·DOI

Galectin-7 Induction by EHMT2 Inhibition Enhances Immunity in Microsatellite Stability Colorectal Cancer.

Sun L, Liu R, Wu ZJ, Liu ZY, Wan AH, Yan S, Liu C, Liang H, Xiao M, You N, Lou Y, Deng Y, Bu X, Chen D, Huang J, Zhang X, Kuang DM, Wan G*.

Gastroenterology. 2024 Mar;166(3):466-482.·2024·DOI

2023

Biological informed graph neural network for tumor mutation burden prediction and immunotherapy-related pathway analysis in gastric cancer.

Liu C#, Wan AH#, Liang H#, Sun L, Li J, Yang R, Li Q, Wu R, Hu K, Yang Y, Cai S*, Wan G*, He W*.

Comput Struct Biotechnol J. 2023 Sep 22;21:4540-4551.·2023·DOI

N6-methyladenosine demethylase FTO enhances chemo-resistance in colorectal cancer through SIVA1-mediated apoptosis.

Lin Z, Wan AH, Sun L, Liang H, Niu Y, Deng Y, Yan S, Wang QP, Bu X, Zhang X, Hu K*, Wan G*, He W*.

Mol Ther. 2023 Feb 1;31(2):517-534.·2023·DOI

2022

RNA and RNA Derivatives: Light and Dark Sides in Cancer Immunotherapy.

Deng Y#, Xiao M#, Wan AH#, Li J, Sun L, Liang H, Wang QP, Yin S, Bu X, Wan G*.

Antioxid Redox Signal. 2022 Dec;37(16-18):1266-1290.·2022·DOI

2021

Measurement of Circulating Tumor Cells to Track Hepatocellular Carcinoma Progression After Liver Transplantation-Case Report.

Deng Y, Sun L, Liang H, Cui B, Cui C, Zhao D, Wan A*, Wan G*.

Front Oncol. 2021 Oct 20;11:760765.·2021·DOI

Loss-of-Function Genetic Screening Identifies Aldolase A as an Essential Driver for Liver Cancer Cell Growth Under Hypoxia.

Niu Y, Lin Z, Wan A, Sun L, Yan S, Liang H, Zhan S, Chen D, Bu X, Liu P, Chen C, He W, Lu X, Wan G*.

Hepatology. 2021 Sep;74(3):1461-1479.·2021·DOI

RNA-binding protein RALY reprogrammes mitochondrial metabolism via mediating miRNA processing in colorectal cancer.

Sun L#, Wan A#, Zhou Z, Chen D, Liang H, Liu C, Yan S, Niu Y, Lin Z, Zhan S, Wang S, Bu X, He W, Lu X*, Xu A*, Wan G*.

Gut. 2021 Sep;70(9):1698-1712.·2021·DOI

2020

RNA m6 A methylation regulates sorafenib resistance in liver cancer through FOXO3-mediated autophagy.

Lin Z, Niu Y, Wan A, Chen D, Liang H, Chen X, Sun L, Zhan S, Chen L, Cheng C, Zhang X, Bu X, He W*, Wan G*.

EMBO J. 2020 Jun 17;39(12):e103181.·2020·DOI

2019

The mechanism and research progress of drug resistance of PD-1/PD-L1 immunotherapy in tumors

Yan S, Sun L, Wan G*.

Acta Pharm Sin. 2019, 54(10): 1728-1734·2019·DOI

RNA N6-methyladenosine demethylase FTO promotes breast tumor progression through inhibiting BNIP3.

Niu Y, Lin Z, Wan A, Chen H, Liang H, Sun L, Wang Y, Li X, Xiong XF, Wei B*, Wu X*, Wan G*.

Mol Cancer. 2019 Mar 28;18(1):46.·2019·DOI