梁衡

Publications

2026

Engineering bacterial nanosyringes for regional immune recalibration at the oral barrier

Wan AH, Liang H, Yan S, Xiao M, Liu R, Wan G*

Oral Sci Homeost Med. 2026 May; 2(2): 9610055.·2026·DOI

Dual-system engineered bacteria and dendritic cells enable precise intratumoral IL-12 delivery and potent antitumor immunity.

Deng Y#, Liang H#, Wan AH#, Liu C#, Yan S#, Li J, Xiao M, Zhou Q, Liu R, Zhang Z, Zhang H, Cheng H, Fu C, Yao Q, Fang J, Neumann S, Wang Q, Huang J*, Wang Z*, Wan G*.

Cell Rep Med. 2026 Jun 16;7(6):102801.·2026·DOI

HNRNPA2B1 Orchestrates Immune Evasion in Colorectal Cancer by Rewiring Tumor-Immune Cell Interactions and Suppressing CD8+ T-cell Infiltration.

Liu C, Liang H, Wang P, Xiao M, Zheng Y, Yan S, Deng Y, Liu R, Wan AH, Wang Z*, Lu X*, Song W*, He W*, Wan G*.

Cancer Immunol Res. 2026 Jan 8;14(1):60-76.·2026·DOI

2025

Non-stoichiometric Sodium Chloride Reprograms Ionic Homeostasis to Enhance Antitumor Immunity.

Wang C#, Deng Y#, Liang H#, Wan AH#, Yan S, Xiao M, Liu C, Fang J, Wang Z*, Wan G*.

MedComm (2020). 2025 Nov 29;6(12):e70534.·2025·DOI

Proviral Integration Site for Moloney Murine Leukemia Virus 2 Suppresses Fibronectin 1 to Drive Adhesion Loss and Epithelial-Mesenchymal Transition in Multiple Myeloma.

Mai J#, Liang H#, Wan AH#, Xiao M#, Zhang H, Deng Y, Yan S, Wan G*, Zheng Y*.

ACS Pharmacol Transl Sci. 2025 Oct 27;8(11):3835-3843.·2025·DOI

Machine learning-assisted tacrolimus dose optimization in childhood- onset systemic lupus erythematosus through population pharmacokinetic modeling.

Liang H#, Xuan Q#, Liu C#, Wan A#, You N, Xiao M, Zhang H, Han M, Wan G*.

Comput Biol Med. 2025 Sep;196(Pt B):110782.·2025·DOI

Decoding the m6A epitranscriptomic landscape for biotechnological applications using a direct RNA sequencing approach.

Liu C#, Liang H#, Wan AH#, Xiao M#, Sun L#, Yu Y, Yan S, Deng Y, Liu R, Fang J, Wang Z*, He W*, Wan G*.

Nat Commun. 2025 Jan 18;16(1):798.·2025·DOI

2024

Galectin-7 Induction by EHMT2 Inhibition Enhances Immunity in Microsatellite Stability Colorectal Cancer.

Sun L, Liu R, Wu ZJ, Liu ZY, Wan AH, Yan S, Liu C, Liang H, Xiao M, You N, Lou Y, Deng Y, Bu X, Chen D, Huang J, Zhang X, Kuang DM, Wan G*.

Gastroenterology. 2024 Mar;166(3):466-482.·2024·DOI

2023

Biological informed graph neural network for tumor mutation burden prediction and immunotherapy-related pathway analysis in gastric cancer.

Liu C#, Wan AH#, Liang H#, Sun L, Li J, Yang R, Li Q, Wu R, Hu K, Yang Y, Cai S*, Wan G*, He W*.

Comput Struct Biotechnol J. 2023 Sep 22;21:4540-4551.·2023·DOI

N6-methyladenosine demethylase FTO enhances chemo-resistance in colorectal cancer through SIVA1-mediated apoptosis.

Lin Z, Wan AH, Sun L, Liang H, Niu Y, Deng Y, Yan S, Wang QP, Bu X, Zhang X, Hu K*, Wan G*, He W*.

Mol Ther. 2023 Feb 1;31(2):517-534.·2023·DOI

2022

RNA and RNA Derivatives: Light and Dark Sides in Cancer Immunotherapy.

Deng Y#, Xiao M#, Wan AH#, Li J, Sun L, Liang H, Wang QP, Yin S, Bu X, Wan G*.

Antioxid Redox Signal. 2022 Dec;37(16-18):1266-1290.·2022·DOI

2021

Measurement of Circulating Tumor Cells to Track Hepatocellular Carcinoma Progression After Liver Transplantation-Case Report.

Deng Y, Sun L, Liang H, Cui B, Cui C, Zhao D, Wan A*, Wan G*.

Front Oncol. 2021 Oct 20;11:760765.·2021·DOI

Loss-of-Function Genetic Screening Identifies Aldolase A as an Essential Driver for Liver Cancer Cell Growth Under Hypoxia.

Niu Y, Lin Z, Wan A, Sun L, Yan S, Liang H, Zhan S, Chen D, Bu X, Liu P, Chen C, He W, Lu X, Wan G*.

Hepatology. 2021 Sep;74(3):1461-1479.·2021·DOI

RNA-binding protein RALY reprogrammes mitochondrial metabolism via mediating miRNA processing in colorectal cancer.

Sun L#, Wan A#, Zhou Z, Chen D, Liang H, Liu C, Yan S, Niu Y, Lin Z, Zhan S, Wang S, Bu X, He W, Lu X*, Xu A*, Wan G*.

Gut. 2021 Sep;70(9):1698-1712.·2021·DOI

2020

RNA m6 A methylation regulates sorafenib resistance in liver cancer through FOXO3-mediated autophagy.

Lin Z, Niu Y, Wan A, Chen D, Liang H, Chen X, Sun L, Zhan S, Chen L, Cheng C, Zhang X, Bu X, He W*, Wan G*.

EMBO J. 2020 Jun 17;39(12):e103181.·2020·DOI

2019

RNA N6-methyladenosine demethylase FTO promotes breast tumor progression through inhibiting BNIP3.

Niu Y, Lin Z, Wan A, Chen H, Liang H, Sun L, Wang Y, Li X, Xiong XF, Wei B*, Wu X*, Wan G*.

Mol Cancer. 2019 Mar 28;18(1):46.·2019·DOI